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Dr. Robert C.G. Martin, Co-Principal Investigator of the DIRECT Study

UofL Department of Surgery Announces First Patient Enrolled in NanoKnife® DIRECT Clinical Study for the Treatment of Stage III Pancreatic Cancer

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Chairman of Department Named President of the Southern Surgical Association

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ULH Operating Suites Renamed the Frank B. Miller, MD Operating Suites

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Dr. Bradon Wilhelmi Receives KMA Educational Achievement Award

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Department Coordinator Debbie Krause Wins Lifetime Achievement Award

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From the Chairman

The University of Louisville, Department of Surgery, has a long and proud tradition of excellence. From its inception in 1837, when the University of Louisville served as the premier medical training ground for the western frontier of the United States, the Department. Surgery has been at the forefront of surgical education, patient care, and research.
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Dr. McMasters

Grand Rounds Calendar

Grand Rounds Speaker

Aug 23, 2019: To Be Announced

Presentation by:
Dr. Nick Nash

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Owen Frederick McMasters

For information on Brown Cancer Center Owen's Wish Fund for Cancer Immunotherapy Research, click here .

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Dr. Robert C.G. Martin, Co-Principal Investigator of the DIRECT Study

UofL Department of Surgery Announces First Patient Enrolled in NanoKnife® DIRECT Clinical Study for the Treatment of Stage III Pancreatic Cancer

University of Louisville Department of Surgery recently announced enrollment of the first patient in AngioDynamics’ NanoKnife® Irreversible Electroporation (IRE) "Data IRECancer Treatment” clinical study (DIRECT).

The DIRECT Study supports a proposed expanded indication for the NanoKnife System in the treatment of Stage III pancreatic cancer.

"We are pleased to be the first enrolling site. The DIRECT Study represents an important milestone in the standardization of care for patients with Stage III pancreatic cancer. Our goal is to generate important data that should standardize and optimize the use of IRE in the treatment of locally advanced pancreatic cancer, significantly improving outcomes for patients with this late-stage diagnosis," said Dr. Robert C.G. Martin, Co-Principal Investigator of the DIRECT Study, Director, Division of Surgical Oncology
 and Professor of Surgery at the University of Louisville and surgical oncologist with UofL Physicians – Surgical Oncology.

AngioDynamics’ DIRECT clinical study features a comprehensive data collection strategy that will provide meaningful clinical information to healthcare professionals, support a regulatory indication for the treatment of Stage III pancreatic cancer, and facilitate reimbursement for hospitals and treating physicians. The next-generation study is classified as a Category B IDE by the FDA, which allows participating sites to obtain coverage for procedures performed in addition to any related routine costs.

"The enrollment of our first patient soon after receiving FDA approval is a strong signal that clinicians are eager to evaluate treatment alternatives that improve the dismal prognosis for Stage III pancreatic cancer patients," said Brent Boucher, AngioDynamics Senior Vice President and General Manager of Oncology. "We look forward to confirming that our proprietary NanoKnife technology offers a compelling alternative to the current standard of care and believe that this study will provide a pivotal dataset for claims and reimbursement purposes."

The DIRECT Study comprises a Randomized Controlled Trial at up to 15 sites, as well as a Real-World Evidence, next-generation registry at up to 30 sites, each with a NanoKnife System treatment arm and a control arm. AngioDynamics expects each NanoKnife arm to consist of approximately 250 patients with an equal number of control patients. The primary endpoint of the study is overall survival.



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Frank B. Miller, M.D. Surgical Suite

ULH Operating Suites Renamed the Frank B. Miller, MD Operating Suites

On July 18, the operating suites at University of Louisville Hospital were officially renamed the Frank B. Miller, MD Operating Suites in honor of the venerable Dr. Frank Miller, dedicated teacher, surgeon and humanitarian who committed much of his life to giving back through teaching and medical mission work. An accomplished surgeon and academician, Dr. Miller's kindness toward others shined bright throughout his life.

Dr. Frank Miller was an Indiana native and graduate of Indiana University School of Medicine. He served a tour of duty in Vietnam, where he was a captain, prior to general surgery residency at the University of Louisville. He joined the University of Louisville Department of Surgery faculty in 1984.

Dr. Miller rose to the rank of Professor of Surgery, where he enjoyed a distinguished career as a surgeon and educator, and served as Chief of Surgery at University of Louisville Hospital for more than a decade. He was Chief of General Surgery, Director of Surgical Education and Director of Trauma.

Dr. Miller was a highly respected surgeon who was a member of several prestigious surgical societies. He had numerous leadership roles on a local, state and national level and lectured throughout the world. He published more than 100 scientific articles and book chapters and received innumerable teaching awards—so many that one such award was subsequently named in his honor. Dr. Miller had a long history of international medical service in third-world countries on three continents.

Dr. Miller was the safety net for a generation of surgical residents, who always called upon him to help with the most difficult situations. He practiced general, vascular and trauma surgery with the greatest skill and compassion imaginable. He improved or saved the lives of innumerable patients. He was adored by an entire generation of medical students, residents, fellows, nurses and other healthcare professionals for his teaching skill and compassion. His service to University of Louisville Hospital was unrivaled.

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Dr. Bradon Wilhelmi at the KMA Annual Meeting

Dr. Bradon Wilhelmi Receives KMA Educational Achievement Award

The Kentucky Medical Association presented its Educational Achievement Award to Bradon Wilhelmi, MD at the 2018 KMA Annual Meeting on Aug. 25.

The award is presented to individuals who have made outstanding contributions and achievements in the area of continuing medical education. Dr. Wilhelmi is a Chair of the Division of Plastic and Reconstructive Surgery.

He was recognized for his efforts to revitalize UofL’s Plastic Surgery Residency program. Since joining the faculty in 2007, Dr. Wilhelmi worked to revamp the program, and since his changes were implemented, the program’s annual in-service scores have improved by 200 percent, and the board pass rate has been 100 percent since he came to the Department. His mentorship of students involved in research projects has culminated in 100 scientific research publications and 25 textbook chapters. He was lauded by colleagues for having a passion and dedication to teaching and has mentored more than 25 residents and 75 medical students.

“Dr. Wilhelmi carries substantial teaching responsibilities, which he fulfills in an outstanding manner," said colleague and KMA past-president Gordin Tobin, MD. “The formal teaching programs and quizzes he organizes are most effective in keeping our residents broadly informed and up-to-date, as demonstrated by our residents’ high performance level on in-service and Board examinations, as well as in clinical skill evaluations.”

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Debbie Krause

Department Coordinator Debbie Krause
Wins Lifetime Achievement Award

Debbie Krause, Department of Surgery coordinator, received the inaugural Dean’s Lifetime Achievement Award at the UofL School of Medicine Dean’s Appreciation Reception, Nov. 13. The Dean’s Lifetime Achievement Award was created by School of Medicine Dean Toni Ganzel, MD, as a special recognition for employees who have served the school with excellence for many years. Debbie has worked for the Department of Surgery for nearly 45 years. During her tenure, she has completed a variety of tasks in service to UofL with the greatest loyalty, professionalism, competence and grace.

“Debbie exemplifies the excellence we strive to achieve in the department. Throughout the course of her career, Debbie has always paid meticulous attention to detail and plans well in advance for every possible contingency. She is the consummate ambassador for the University, as she is our liaison with countless other institutions and leaders in American medicine and surgery,” said Kelly McMasters, MD, PhD, Chairman of the Department of Surgery. “She exudes warmth for our medical students and residents, as well as new and veteran faculty and co-workers. She remembers the names of their spouses and children, as well as special details about each and every one of them. For her role in coordinating our visiting lectureships and grand rounds programs, Debbie is the perfect host and continually receives letters of praise from visiting professors and their staff.”

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